A study led by Dr. Rebecca Olson, the Gale lab shows that HIV latency and viral suppression each link with cell-intrinsic defects in specific innate immune gene expression. We identify a set of innate immune effector genes as candidate viral latency restriction factors whose expression and function could possibly mitigate establishing latent HIV infection.
Read the study: https://retrovirology.biomedcentral.com/articles/10.1186/s12977-022-00599-z
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