2016

Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population.

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, Pardo-Manuel de Villena F, Baric RS, Heise MT, Gale M Jr.
Genom Data. 2016 Oct 14;10:137-140. eCollection 2016 Dec. PMID: 27872814

Identifying protective host gene expression signatures within the spleen during West Nile virus infection in the collaborative cross model.

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, de Villena FP, Baric R, Heise M, Gale M Jr.
Genom Data. 2016 Oct 14;10:114-117. eCollection 2016 Dec. PMID: 27843766

Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling.

Jarret A, McFarland AP, Horner SM, Kell A, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale M Jr, Savan R.
Nat Med. 2016 Dec;22(12):1475-1481. PMID: 27841874

A Mouse Model of Chronic West Nile Virus Disease.

Graham JB, Swarts JL, Wilkins C, Thomas S, Green R, Sekine A, Voss KM, Ireton RC, Mooney M, Choonoo G, Miller DR, Treuting PM, Pardo Manuel de Villena F, Ferris MT, McWeeney S, Gale M Jr, Lund JM.
PLoS Pathog. 2016 Nov 2;12(11):e1005996. PMID: 27806117

Interferon lambda 4 expression is suppressed by the host during viral infection.

Hong M, Schwerk J, Lim C, Kell A, Jarret A, Pangallo J, Loo YM, Liu S, Hagedorn CH, Gale M Jr, Savan R.
J Exp Med. 2016 Nov 14;213(12):2539-2552. Epub 2016 Oct 31. PMID: 27799623

Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate.

Adams Waldorf KM, Stencel-Baerenwald JE, Kapur RP, Studholme C, Boldenow E, Vornhagen J, Baldessari A, Dighe MK, Thiel J, Merillat S, Armistead B, Tisoncik-Go J, Green RR, Davis MA, Dewey EC, Fairgrieve MR, Gatenby JC, Richards T, Garden GA, Diamond MS, Juul SE, Grant RF, Kuller L, Shaw DW, Ogle J, Gough GM, Lee W, English C, Hevner RF, Dobyns WB, Gale M Jr, Rajagopal L.
Nat Med. 2016 Nov;22(11):1256-1259. PMID:  27618651

Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6.

Liu HM, Jiang F, Loo YM, Hsu S, Hsiang TY, Marcotrigiano J, Gale M Jr.
EBioMedicine. 2016 Jul;9:195-206.  PMID: 27372014

MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis.

Zhao J, Vijay R, Zhao J, Gale M Jr, Diamond MS, Perlman S.
J Virol. 2016 Jul 27;90(16):7098-108. PMID: 27226371

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.

Wang F, Alain T, Szretter KJ, Stephenson K, Pol JG, Atherton MJ, Hoang HD, Fonseca BD, Zakaria C, Chen L, Rangwala Z, Hesch A, Chan ESY, Tuinman C, Suthar MS, Jiang Z, Ashkar AA, Thomas G, Kozma SC, Gale M Jr, Fitzgerald KA, Diamond MS, Mossman K, Sonenberg N, Wan Y, Lichty BD.
Nat Immunol. 2016 May;17(5):514-522.  PMID: 27043414

Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway.

Green RR, Wilkins C, Pattabhi S, Dong R, Loo Y, Gale M Jr.
Genom Data. 2016 Feb 1;7:290-2. PMID:  26981429

The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites.

Neufeldt CJ, Joyce MA, Van Buuren N, Levin A, Kirkegaard K, Gale M Jr, Tyrrell DL, Wozniak RW.
PLoS Pathog. 2016 Feb 10;12(2):e1005428. PMID: 26863439