Influenza virus infection causes significant illness and death globally each year despite the existence of a vaccine. Our work has sought to understand the innate immune determinates that are able to regulate the induction of protective adaptive immune responses against influenza in order to inform novel therapeutic and adjuvant strategies. We recently published a study revealing that the innate immune cytokine IFN-lambda acts on DC and is required for generation of optimal CD8 T cell-mediated protection against influenza virus infection in a murine model (DOI:10.1038/s41590-019-0408-z).
Save the Date! On November 1-4, 2020, the International Cytokine and Interferon Society (ICIS) will be hosting its 8th annual meeting Cytokines 2020: Structure-Function and Systems Biology of Cytokines in Seattle, Washington.
We would like to invite you to take part of this important conference.
This meeting will explore the application of molecular and systems biology approaches to understand the mechanisms of cytokine functions in the broad areas of signal transduction, gene expression, and systems responses in the context of health and disease.
For multiple years the Gale Lab continues as one of the most highly cited laboratories in infectious disease and immunology research in the world.
This highly anticipated annual list identifies scientists and social scientists who produced multiple papers ranking in the top 1% by citations for their field and year of publication, demonstrating significant research influence among their peers. Read more about the methodology here.
Wound repair of mucous tissues during early infection by Simian Immunodeficiency Virus guards some primate species from contracting AIDS, a study has learned. The researchers looked at why certain species can carry SIV throughout their lives without getting AIDS.
SIV is closely related to HIV, or the Human Immunodeficiency Virus, and has become a laboratory model for studies seeking AIDS and HIV cures and prevention.
Dr. Alison Kell has earned a NIAID K22 career transition award for her work on innate immune recognition of hantaviruses!